Xanthene dyes

Details Xanthene dyes Xanthene dyes

2008-03-18

2008-03-18

Jones, Dameron L. (Department: 1618)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

C424S001110, C424S001650, C424S009100, C424S009200, C549S388000

Reexamination Certificate

active

07344701

ABSTRACT:
The invention provides a novel class of xanthene dyes, some of which are functionalized to allow their coupling to conjugation partners of interest, e.g. biomolecules, drugs, toxins and the like. Also provided are conjugates of the dyes, methods of preparing and using the dyes and their conjugates and kits including the dyes and their conjugates.

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patent: 6399392 (2002-06-01), Haugland et al.
Maciej Adamczyk and Jonathan Grote, “Efficient Fluorescein Spirolactam and Bis-Spirolactam Synthesis”,Synthetic Communications, 31(17), 2681-2690, (2001).
Troy A. Walton, et al. “Evaluation of New Linkers and Synthetic Methods for Internal Modified Oligonucleotides”,Bioconjugate Chemistry, vol. 13, 1155-1158 (2002).

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