Xanthene and thioxanthene derivatives, compositions thereof and

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Allergen or component thereof

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260328, 260335, 424283, C07D31190

Patent

active

040355039

ABSTRACT:
The present invention relates to novel xanthene and thioxanthene derivatives of the following general formula: ##STR1## wherein Y represents sulfur or oxygen, R.sup.1 represents hydrogen, chlorine, trifluoromethyl or dimethylsulfamoyl, R.sup.2 represents hydrogen or fluorine; and R.sup.3 and R.sup.4 each represents hydrogen or methyl, provided that R.sup.3 and R.sup.4 may not both represent hydrogen, or R.sup.3 and R.sup.4 taken together with the nitrogen atom form a piperazine or piperidine ring optionally substituted in the 4-position by a methyl group or a 2-hydroxyethyl group, if desired, esterified with an aliphatic carboxylic acid having from one to seventeen carbon atoms inclusive, as well as non-toxic acid addition salts thereof.

REFERENCES:
patent: 2951082 (1960-08-01), Spraque et al.
patent: 3192204 (1965-06-01), Craig et al.
patent: 3282930 (1966-11-01), Craig et al.
patent: 3310553 (1967-03-01), Bloom et al.
patent: 3374231 (1968-03-01), Cusic et al.
patent: 3681346 (1972-08-01), Petersen et al.

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