Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Reexamination Certificate
2006-10-03
2006-10-03
Wax, Robert A. (Department: 1653)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
C424S001690
Reexamination Certificate
active
07115708
ABSTRACT:
The present invention is directed to β-superfamily conotoxin peptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated ion channels, ligand gated channels and other receptors. The invention is further directed to nucleic acid sequences encoding the β-superfamily conotoxin peptides and encoding β-superfamily conotoxin propeptides, as well as the β-superfamily conotoxin propeptides.
REFERENCES:
patent: 5595972 (1997-01-01), Olivera et al.
patent: WO 00/20444 (2000-04-01), None
McIntosh, J. Michael et al., “ConusPeptides as Probes for Ion Channels,” Methods in Enzymology, vol. 294, pp. 605-624, 1999.
Garrett James E.
Jones Robert M.
Olivera Baldomero M.
Watkins Maren
Cognetix, Inc.
Rothwell Figg Ernst & Manbeck
University of Utah Research Foundation
Wax Robert A.
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