β-sheet mimetics and composition and methods relating...

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

Reexamination Certificate

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C514S183000, C514S221000, C514S248000, C540S473000, C540S568000

Reexamination Certificate

active

07053214

ABSTRACT:
Compounds having the following structure:including pharmaceutically acceptable salts and stereoisomers thereof, wherein A, A′, B, X, Y, R2, R3, R4and R5are as defined herein. Such compounds have utility over a wide range of applications, including use as diagnostic and therapeutic agents. In particular, compounds of this invention, and pharmaceutical compositions containing such compounds, are tryptase antagonists.

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