β-lactamase inhibitors and methods of use thereof

Details β-lactamase inhibitors and methods of use thereof β-lactamase inhibitors and methods of use thereof

2007-02-27

2007-02-27

McKane, Joseph K. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Boron containing doai

C568S003000, C560S008000

Reexamination Certificate

active

10866179

ABSTRACT:
The invention provides novel non-β-lactam inhibitors of β-lactamases. In particular, the invention provides boronic acid-based compounds set forth in the specification. These compounds may be used with β-lactam antibiotics to bacterial infection, particularly, β-lactam-antibiotic-resistant bacterial infections. These compounds are also antibacterial agents by themselves. The invention further provides methods of using such compounds. Finally, the invention provides a pharmaceutical composition comprising these compounds.

REFERENCES:
patent: 6075014 (2000-06-01), Weston et al.
patent: 6417174 (2002-07-01), Shoichet et al.

Affiliated with

Also associated with

Rating

β-lactamase inhibitors and methods of use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with β-lactamase inhibitors and methods of use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and β-lactamase inhibitors and methods of use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3828667