Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-01-16
2007-01-16
Shameeh, Golam M. M. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S350000
Reexamination Certificate
active
10416334
ABSTRACT:
1. A β-lactam compound of the formula [1];wherein R1is a lower alkyl, a lower alkyl substituted by a hydroxy; R2is a hydrogen, a lower alkyl; X is O, S, NH; m and n are 0 to 4, Y1is a halogen, cyano, a hydroxy, an amino, a lower alkyloxy, a lower alkylamino, a carboxy, a carbamoyl, a lower alkyl, etc., Y2is hydrogen, an alkyl, cyano, —C(R3)═NR4(wherein R3and R4are hydrogen, an amino, an alkyl, etc., or R3and R4may combine each other together with the nitrogen atom to form a 5- to 7-membered heterocyclic group), or a pharmaceutically acceptable salt thereof, or a non-toxic ester thereof, which has an excellent antibacterial activity against Gram-positive bacteria, especially against MRSA and MRCNS.
REFERENCES:
patent: 5750686 (1998-05-01), Sunagawa et al.
patent: 0 704 446 (1996-04-01), None
patent: 98/09965 (1998-03-01), None
Goetschi Erwin
Itoh Masanori
Kubota Katsumi
Sunagawa Makoto
Dainippon Sumitomo Pharma Co. ,Ltd.
Sackey Ebenezer
Shameeh Golam M. M.
Wenderoth , Lind & Ponack, L.L.P.
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