β-L-2'-deoxy-nucleosides for the treatment of HIV...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

Reexamination Certificate

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C424S464000, C424S449000, C424S422000, C424S423000

Reexamination Certificate

active

06896900

ABSTRACT:
Compounds and pharmaceutical compositions active against HIV are provided, as is a method for the treatment of HIV infection in humans and other host animals is provided comprising administering an effective amount of a β-L-(2′ or 3′-azido)-2′,3′-dideoxy-5-fluorocytosine of the formulawherein R is H, acyl, monophosphate, diphosphate, or triphosphate, or a stabilized phosphate derivative (to form a stabilized nucleotide prodrug), and R′ is H, acyl, or alkyl.

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