βGBP, compositions comprising βGBP, and related...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S350000

Reexamination Certificate

active

07994113

ABSTRACT:
The invention relates to β-galactoside binding protein (βGBP) and compositions, including pharmaceutical compositions, comprising βGBP for use in therapy and related applications. In particular, the invention relates to use of βGBP and the manufacture of medicaments for the treatment or prevention of conditions in which disease associated cell division occurs, wherein the cells which result from said disease associated cell division comprise a cell in respect of which the effect of βGBP is not inhibition of growth. The invention also relates to methods of inducing apoptosis, methods of treating or preventing conditions in which disease associated cell division occurs and methods of assessing the suitability of βGBP as a therapeutic agent.

REFERENCES:
patent: 5587460 (1996-12-01), Nedwin et al.
patent: 5948628 (1999-09-01), Cummings et al.
patent: 6127169 (2000-10-01), Mallucci et al.
patent: 2249312 (1992-05-01), None
patent: WO 92/07938 (1992-05-01), None
Horiguchi et al. 2003; Galectin-1 inducescell adhesion to the extracellular matrix and apoptosis of non-adherent human colon cncer Colo201 cells. J. Biochemistry 134(6): 869-874.
Baatar, D. et al (2007) Journal of Immun vol. 178 pp. 1-2.
Blaser, C. et al (1998) Eur J Immunol 28: 2311-2319.
Johnstone, RW et al. (2002) Cell 108: 153-164.
Mallucci, L. et al. (2003). Biochem. Pharmacol vol. 66 pp. 1563-1569.
Mallucci, L. et al. J. (2004) Immunotherap. vol. 27 p. S55.
Mallucci, L. et al. (2005) Curr. Opinion Invest. Drugs vol. 6 pp. 1228-1233.
Mallucci, L. et al. (2006) Journal of Immunotherapy vol. 29 p. 675.
Mallucci, L. and Wells, (2007)Apoptosis, Cell Signaling and Human Diseases: Molecular Mechanisms, Humana Press p. 203-216.
Mazurek, N. et al (2007) Journal of Biol Chem pp. 1-25.
Rabinovich, GA et al. (1997) J. Biochem 122: 365-373.
Rabinovich, GA et al. (1998) J. Immunol. 160: 4831-4840.
Rabinovich, GA et al. (1999) J. Exp. Med. 190: 385-397.
Ravatn, R. et al. (2005) Cancer Res. vol. 65 pp. 1631-1634.
Spellacy, N. et al. (2002) Br. J. Cancer vol. 86 p. S21, Abs No. 4.3.
Tsuboi, K. et al (2007) Anticancer Research vol. 27 pp. 2289-2296.
Wells, V and Mallucci, L. (1991) Cell 64: 91-97.
Wells, V. et al (1999) Eur J. Cancer, vol. 35 pp. 978-983.
Wells, V. et al. (2002) Br. J. Cancer vol. 86 p. S85, Abs No. P167.
Wells, V. et al (2007) Oncogene vol. 26 pp. 7709-7714.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

βGBP, compositions comprising βGBP, and related... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with βGBP, compositions comprising βGBP, and related..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and βGBP, compositions comprising βGBP, and related... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2763890

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.