Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2007-12-25
2007-12-25
Goldberg, Jeanine A. (Department: 1634)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S006120, C536S024300
Reexamination Certificate
active
10659583
ABSTRACT:
The present invention relates to a β-catenin oligonucleotide microchip for detecting mutation in the mutational hot spot regions of β-catenin gene, a manufacturing process thereof and a method for detecting the β-catenin mutation employing same, wherein specific oligonucleotides are selectively designed to detect various missense mutations and in-frame deletion at the mutational hot spots of β-catenin gene. The β-catenin oligo chip of the present invention can be used in studies to detect β-catenin mutations and unravel the signal transduction mechanism and tumorigenesis related to β-catenin gene.
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Kang Hio-Chung
Kim Il-Jin
Park Jae-Gahb
Park Jae-Hyun
Anderson Kill & Olick PC
National Cancer Center
Salmon Katherine
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