Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-10-11
2005-10-11
McKenzie, Thomas C. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S255050, C514S332000, C514S335000, C514S336000, C514S338000, C514S341000, C514S342000, C514S343000, C544S212000, C544S405000, C546S261000, C546S267000, C546S268700, C546S269100, C546S269700, C546S275400, C546S282100, C546S323000
Reexamination Certificate
active
06953798
ABSTRACT:
Alkanoic acid derivatives of formula (1) are described:in-line-formulae description="In-line Formulae" end="lead"?Ar1(Alka)rL1Ar2CH(R1)C(Ra)(Ra′)R (1)in-line-formulae description="In-line Formulae" end="tail"?Ar1is an optionally substituted aromatic or heteroarotic group;L1is a covalent bond or a linker atom or group;Ar2is an optionally substituted phenylene or nitrogen-containing six-membered heteroarylene group;R is a carboxylic acid (—CO2H) or a derivative thereof;and the salts, solvates, hydrates and N-oxides thereof.The compounds are able to inhibit the binding of α4 integrins to their ligands and are of use in the prophylaxis and treatment of immune or inflammatory disorders.
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Archibald Sarah Catherine
Head John Clifford
Porter John Robert
Warrellow Graham John
Celltech R&D Limited
McKenzie Thomas C.
Woodcock & Washburn LLP
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