β1,3-galactosyltransferase and DNA encoding the enzyme

Details β1,3-galactosyltransferase and DNA encoding the enzyme β1,3-galactosyltransferase and DNA encoding the enzyme

2005-12-13

2005-12-13

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

C435S071200, C435S252300, C435S320100, C435S252330, C435S072000, C435S074000, C435S069100, C435S325000, C536S023200, C536S023700

Reexamination Certificate

active

06974687

ABSTRACT:
The present invention provides a protein having β1,3-galactosyltransferase activity, a DNA encoding the protein, a transformant comprising the DNA, a process for producing the protein using the transformant, and a process for producing a galactose-containing complex carbohydrate using the transformant.

REFERENCES:
patent: 5395757 (1995-03-01), Hayakawa et al.
Bailly et.al. Characterization and specific assay for a galactoside beta-3-galactosyltransferase□□of human kidney. EEur. Journal of Biochemistry, vol. 173, Apr. 15, 1988, pp. 417-422.
Basu SS, Dastgheib S, Ghosh S, Basu M, Kelly P, Basu S. Purification and characterization of avian glycolipid: beta-galactosyltransferases (GalT-4 and GalT-3): cloning and expression of truncated betaGalT-4. Acta Biochim Pol. 1998;45(2):451-67.
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Linton, et al., “Phase variation of a β-1,3 galactosyltransferase involved in generation . . . ”,Molecular Microbiology, vol. 37, No. 3 (2000), pp. 501-514.
Shib S. Basu et al., “Purification and Characterization of Avian Glycolipid: β-Galactosyltransferases (GaIT-4 and GaIt-3): Cloning and Expression of Truncated βGaIT-4”,Acta Biochimica Polonica, vol. 45, No. 2, 1998, pp. 451-467.
Hiroshi Miyazaki et al., “Expression Cloning of Rat cDNA Encoding UDP-galactose:GD2β1, 3-Galactosyltransferase That Determines the Expression of GD1b/GM1/GA1”,The Journal of Biological Chemistry, vol. 272, No. 40, Oct. 1997, pp. 24794-24799.
Sujoy Ghosh et al., “Purification, Properties, and Immunological Characterization of GaIT-3 (UDP-galactose: GM2 Ganglioside, β1-3 Galactosyltransferase) From Embryonic Chicken Brain”,Glycoconjugate Journal, vol. 12, No. 6, 1995, pp. 838-847.
Pascal Bailly et al., “Characterization and Specific Assay for a Galactoside β-3-Galactosyltransferase of Human Kidney”,Eur. Journal of Biochemistry, vol. 173, Apr. 15, 1988, pp. 417-422.

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