α-β C4BP-type recombinant heteromultimeric proteins

Details α-β C4BP-type recombinant heteromultimeric proteins α-β C4BP-type recombinant heteromultimeric proteins

2006-07-11

2006-07-11

Mertz, Prema (Department: 1646)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fusion protein or fusion polypeptide

C530S350000, C435S069700, C435S071100, C435S071200, C435S325000, C435S320100, C435S810000

Reexamination Certificate

active

07074411

ABSTRACT:
A recombinant heteromultimeric protein including at least (a) a polypeptide fusion molecule A consisting of a C4BP α-chain C-terminal fragment and a polypeptide fragment heterologous to said α-chain, and (a) a polypeptide fusion molecule B consisting of a C4BP β-chain C-terminal fragment and a polypeptide fragment heterologous to said β-chain, wherein (a) and (b) are linked in the C-terminal portion to form said multimeric protein.

REFERENCES:
patent: 5405946 (1995-04-01), Griffin et al.
patent: 5679546 (1997-10-01), Ko et al.
patent: 5851528 (1998-12-01), Ko et al.
Haynes, B. F. et al., Update on Issues of HIV Vaccine Development, The Finnish Medical Society DUODECIM, Ann Med', vol. 28, pp. 39-41 Med, 1996.
Fahey, J. L. et al., Status of Immune-based Therapies in HIV Infection and AIDS, Clin. Exp. Immunol., vol. 88, pp. 1-5, 1992.
Rudinger, J et al., Peptide Hormones, ed. J. A. Parsons, University Park Press, Baltimore, pp. 1-7, 1976.
Hillarp et al., Proc Natl Acad Sci 1990, vol. 87(3): pp. 1183-1187, esp. p. 1186: Figure 6.
Horst Ibelgaufts, Dictionary of Cytokines 1995, VCH Publishers, Inc., New York, NY, esp. pp. 123 and 126.
Anderson et al., J. Biol. Chem., “High affinity binding of human vitamin K-dependent protein S to a truncated recombinant beta-chain of C4b-binding protein expressed inEscherichia coli”, Feb. 1993, 268, (5) P3033-6.
WO, A, 91 11461 (Biogen Inc.) Aug. 1991.
Morris, C., ed.Dictionary of Science and Technology, Academic Press, San Diego, Federal Register, Uniform Biological Material Transfer Agreement: Discussion of Public Comments Received; Publication of Final Format of the Agreement, Mar. 8, 1995, pp. 12771-12775.
Weir's Handbook of Experimental Immunology, 5thedition,Cell Surface and Messenger Molecules of the Immune System, Herzenberg, Stanford, CA, vol. II, Chapter 6, pp. 61.1-61.3, 61.13-61.14, 61.24-61.25.
The Leucocyte Antigen Facts Book, 2ndedition, Barclay et al., eds., Academic Press, San Diego, CA, pp. 2-17.

Affiliated with

Also associated with

Rating

α-β C4BP-type recombinant heteromultimeric proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with α-β C4BP-type recombinant heteromultimeric proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and α-β C4BP-type recombinant heteromultimeric proteins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3560826