Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Reexamination Certificate
2007-07-31
2007-07-31
Achutamurthy, P. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
C435S440000, C435S252300, C435S320100, C435S069100, C435S071100, C435S025000, C536S023700, C536S023200
Reexamination Certificate
active
10619779
ABSTRACT:
The present invention provides an α-keto acid reductase isolated fromLeuconostoc mesenteroidessubsp.dextranicum, and a DNA encoding the reductase. The enzyme and homologs thereof reduce α-keto acids under the presence of NADH to produce optically active α-hydroxy acids. The α-hydroxy acids of the present invention include optically active mandelic acid derivatives of formula II. The optically active mandelic acid derivatives obtained by the present invention are useful as intermediates in synthesizing pharmaceuticals and pesticides
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Kimoto Norihiro
Yamamoto Hiroaki
Achutamurthy P.
Daicel Chemical Industries Ltd.
DiGiorgio Jeanne M.
Lahive & Cockfield LLP
Pak Yong D.
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