α-Glucosidase inhibitors from a natural source

Details α-Glucosidase inhibitors from a natural source α-Glucosidase inhibitors from a natural source

2006-07-25

2006-07-25

Flood, Michele (Department: 1655)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

Containing or obtained from piper

C514S866000

Reexamination Certificate

active

07081260

ABSTRACT:
The present invention relates to a method for providing α-glucosidase inhibition to a subject by administering a pharmaceutical composition comprising a α-glucosidase inhibitory agent selected from pipataline (formula 1a), sesamin (formula 1b), pellitorine (Formula 1c), guineensine (Formula 1d) and brachystamide-B (formula 1e) having therapeutic application for diabetes mellitus, cancer, viral diseases such as hepatitis B and C, HIV, AIDS etc; also the invention provides a process for the isolation of said α-glucosidase inhibitory agent from the plant sourcePiper longumin significant yields.

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