α-Glucosidase inhibitors and their synthesis from a...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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07071341

ABSTRACT:
The present invention provides novel α-glucosidase inhibitory compound (−)-mesquitol and its analogs isolated in significant yield from traditional medicinal plantDichrostachys cinereaand further modification of (−)-mesquitol to enhance the α-glucosidase inhibitory potential; the invention also identifies the usage of (−)-mesquitol and its analogues, based on their α-glucosidase inhibitory activity, as broad based potential therapeutics as antihyperglycernic, antidiabatic, antiobesity, antiviral, anticancer, immunestimulants and the like.

REFERENCES:
Collins, FM ‘Current treatment approaches to type 2 diabetes mellitus: success and shortcomings’ PMID: 12408409 (2002).
Scheen, AJ ‘Treatment of diabetes in patients with severe obesity’ Biomed & Pharmacother (2000) 54:74-79.

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