α- and β-amino acid hydroxyethylamino sulfamic...

Details α- and β-amino acid hydroxyethylamino sulfamic... α- and β-amino acid hydroxyethylamino sulfamic...

2007-04-10

2007-04-10

Morris, Patricia L. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S169000

Reexamination Certificate

active

11167164

ABSTRACT:
Certain Alpha- and Beta-amino acid hydroxyethylamino sulfamic acid derivatives represented by the following formula are useful as retroviral protease inhibitors:

REFERENCES:
patent: 4450164 (1984-05-01), Bristol et al.
patent: 4477441 (1984-10-01), Boger et al.
patent: 4514391 (1985-04-01), Gordon et al.
patent: 4548926 (1985-10-01), Matsueda et al.
patent: 4599198 (1986-07-01), Hoover
patent: 4616088 (1986-10-01), Ryono et al.
patent: 4668769 (1987-05-01), Hoover
patent: 4668770 (1987-05-01), Boger et al.
patent: 4757050 (1988-07-01), Natarajan et al.
patent: 4880938 (1989-11-01), Freidinger
patent: H725 (1990-01-01), Gordon
patent: 4963530 (1990-10-01), Hemmi et al.
patent: 4977277 (1990-12-01), Rosenberg et al.
patent: 5856353 (1999-01-01), Tung et al.
patent: 5977137 (1999-11-01), Tung et al.
patent: 6156768 (2000-12-01), Vazquez et al.
patent: 6444678 (2002-09-01), Vazquez et al.
patent: A-79823/87 (1988-04-01), None
patent: 172347 (1986-02-01), None
patent: 223437 (1987-05-01), None
patent: 0 264 795 (1988-04-01), None
patent: 337714 (1989-10-01), None
patent: 0 342541 (1989-11-01), None
patent: 0 346 847 (1989-12-01), None
patent: 356223 (1990-02-01), None
patent: 389898 (1990-10-01), None
patent: 393445 (1990-10-01), None
patent: 402646 (1990-12-01), None
patent: 468641 (1992-01-01), None
patent: 2184730 (1987-07-01), None
patent: 2200115 (1988-07-01), None
patent: 2209752 (1989-05-01), None
patent: WO84/03044 (1984-08-01), None
patent: WO 92/00750 (1992-01-01), None
patent: WO 92/08699 (1992-05-01), None
patent: 94/05639 (1994-03-01), None
patent: WO 94/05639 (1994-03-01), None
Roberts et al, “Rational Design of Peptide-based Proteinase Inhibitors,” Science, 248, 358 (1990).
Erickson et al, “Design Activity, and 2.8Å Crystal Structure of a C2Symmetric Inhibitor Complexed to HIV-1 Protease,” Science, 249,-527 (1990).
Pearl et al, “Sequence specificity of retroviral proteases” Nature, 328, p. 482 (1987).
Martin, Drugs of the Future, 16(3), 210-212 (1991).
Meek et al,Letter To Nature, 343, 90-92 (1990).
McQuade et al,Science, 274, 454-456 (1990).
Rich et al, Peptide Inhibitors of Proteases, 511-520.
Rosenberg et al,J. Med. Chem., 30, 1224-1228 (1987).
CA 117:49265, toyoda et al. 1992.
CA 115:232882, Fung t al. 1991.
CA 110:173760, 1989.
CA 110:135732, Hagenbach et al. 1989.

Affiliated with

Also associated with

Rating

α- and β-amino acid hydroxyethylamino sulfamic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with α- and β-amino acid hydroxyethylamino sulfamic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and α- and β-amino acid hydroxyethylamino sulfamic... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3721736