α- and β-amino acid hydroxyethylamino...

Details α- and β-amino acid hydroxyethylamino... α- and β-amino acid hydroxyethylamino...

2008-01-22

2008-01-22

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S408000, C548S400000, C546S314000, C546S316000, C546S335000, C546S336000

Reexamination Certificate

active

11526101

ABSTRACT:
α- and β-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.

REFERENCES:
patent: 4450164 (1984-05-01), Bristol et al.
patent: 4477441 (1984-10-01), Boger et al.
patent: 4514391 (1985-04-01), Gordon et al.
patent: 4548926 (1985-10-01), Matsueda et al.
patent: 4599198 (1986-07-01), Hoover
patent: 4616088 (1986-10-01), Ryono et al.
patent: 4668769 (1987-05-01), Hoover
patent: 4668770 (1987-05-01), Boger et al.
patent: 4757060 (1988-07-01), Lukacsko et al.
patent: 4880938 (1989-11-01), Freidinger
patent: H725 (1990-01-01), Gordon
patent: 4963530 (1990-10-01), Hemmi et al.
patent: 4977277 (1990-12-01), Rosenberg et al.
patent: 5585397 (1996-12-01), Tung et al.
patent: 5744481 (1998-04-01), Vazquez et al.
patent: 5786483 (1998-07-01), Vazquez et al.
patent: 5830897 (1998-11-01), Vazquez et al.
patent: 5843946 (1998-12-01), Vazquez et al.
patent: 5968942 (1999-10-01), Vazquez et al.
patent: 6046190 (2000-04-01), Vazquez et al.
patent: 6060476 (2000-05-01), Vazquez et al.
patent: 6172082 (2001-01-01), Vazquez et al.
patent: 6248775 (2001-06-01), Vazquez et al.
patent: 6335460 (2002-01-01), Vazquez et al.
patent: 6417387 (2002-07-01), Vazquez et al.
patent: 6455581 (2002-09-01), Vazquez et al.
patent: 6472407 (2002-10-01), Vazquez et al.
patent: 6500832 (2002-12-01), Vazquez et al.
patent: 6534493 (2003-03-01), Vazquez et al.
patent: 6646010 (2003-11-01), Vazquez et al.
patent: 6846954 (2005-01-01), Vazquez et al.
patent: 6924286 (2005-08-01), Vazquez et al.
patent: 7115618 (2006-10-01), Vazquez et al.
patent: 79823 (1988-04-01), None
patent: 104 041 (1984-03-01), None
patent: 114 993 (1984-08-01), None
patent: 172 347 (1986-02-01), None
patent: 223 437 (1987-05-01), None
patent: 0 264 795 (1988-04-01), None
patent: 337 714 (1989-10-01), None
patent: 342 541 (1989-10-01), None
patent: 346 847 (1989-12-01), None
patent: 356 223 (1990-02-01), None
patent: 389 898 (1990-10-01), None
patent: 393 445 (1990-10-01), None
patent: 393 457 (1990-10-01), None
patent: 402646 (1990-12-01), None
patent: 468641 (1992-01-01), None
patent: 2 184 730 (1987-07-01), None
patent: 2 200 115 (1988-07-01), None
patent: 2 209 752 (1989-05-01), None
patent: WO 84/03044 (1984-08-01), None
patent: WO 92/00750 (1992-01-01), None
patent: WO 92/08599 (1992-05-01), None
Erickson et al., “Design Activity, and 2.8Å Crystal Structure of a C2 Symmetric Inhibitor Complexed to HIV-1 Protease,” Science, 249, 527 (1990).
Martin,Drugs f the Future, 16(3), 210-212 (1991).
McQuade et al.,Science, 247, 454-456 (1990).
Meek et al.,Letter to Nature, 343, 90-92 (1990).
Pearl et al., “Sequence Specificity of Retroviral Proteases,”Nature, 328 (1987).
Rich et al. Peptide Inhibitors of Proteases, 511-520 (1983).
Roberts et al., “Rational Design of Peptide-based Proteinase Inhibitors,”Science, 248, 358 (1990).
Rosenberg et al.,J. Med. Chem., 30, 1224-1228 (1987).

Affiliated with

Also associated with

Rating

α- and β-amino acid hydroxyethylamino... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with α- and β-amino acid hydroxyethylamino..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and α- and β-amino acid hydroxyethylamino... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3928371