α- and β-amino acid hydroxyethylamino...

Details α- and β-amino acid hydroxyethylamino... α- and β-amino acid hydroxyethylamino...

2005-01-25

2005-01-25

McKane, Joseph K. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

Reexamination Certificate

active

06846954

ABSTRACT:
α- and β-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.

REFERENCES:
patent: 4450164 (1984-05-01), Bristol et al.
patent: 4477441 (1984-10-01), Boger et al.
patent: 4514391 (1985-04-01), Gordon et al.
patent: 4548926 (1985-10-01), Matsueda et al.
patent: 4599198 (1986-07-01), Hoover
patent: 4616088 (1986-10-01), Ryono et al.
patent: 4668769 (1987-05-01), Hoover
patent: 4668770 (1987-05-01), Boger et al.
patent: 4757050 (1988-07-01), Natarajan et al.
patent: 4880938 (1989-11-01), Freidinger
patent: H725 (1990-01-01), Gordon
patent: 4963530 (1990-10-01), Hemmi et al.
patent: 4977277 (1990-12-01), Rosenberg et al.
patent: 5585397 (1996-12-01), Tung et al.
patent: 79823 (1988-04-01), None
patent: 104 041 (1984-03-01), None
patent: 114 993 (1984-08-01), None
patent: 172 347 (1986-02-01), None
patent: 223 437 (1987-05-01), None
patent: 0 264 795 (1988-04-01), None
patent: 337 714 (1989-10-01), None
patent: 342 541 (1989-10-01), None
patent: 346 847 (1989-12-01), None
patent: 356 223 (1990-02-01), None
patent: 389 898 (1990-10-01), None
patent: 393 445 (1990-10-01), None
patent: 393 457 (1990-10-01), None
patent: 402646 (1990-12-01), None
patent: 468641 (1992-01-01), None
patent: 2 184 730 (1987-07-01), None
patent: 2 200 115 (1988-07-01), None
patent: 2 209 752 (1989-05-01), None
patent: WO 8403044 (1984-08-01), None
patent: WO 9208599 (1992-05-01), None
Erickson et al., “Design Activity, and 2.8Å Crystal Structure of a C2 Symmetric Inhibitor Complexed to HIV-1 Protease,” Science, 249, 527 (1990).
Martin,Drugs f the Future, 16(3), 210-212 (1991).
McQuade et al.,Science, 247, 454-456, (1990).
Meek et al.,Letter to Nature, 343, 90-92 (1990).
Pearl et al., “Sequence Specificity of Retroviral Proteases,”Nature, 328 (1987).
Rich et al. Peptide Inhibitors of Proteases, 511-520 (1983).
Roberts et al., “Rational Design of Peptide-based Proteinase Inhibitors,”Science, 248, 358 (1990).
Rosenberg et al.,J. Med. Chem., 30, 1224-1228 (1987).

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