Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
C435S007100, C435S007200, C435S007210, C435S007500, C435S007920
The present invention is directed to a screening mechanism for identifying members of the general population at increased risk for alcoholism and premenstrual syndrome. The screening mechanisms may be used to measure the expression of the α4β2δ GABAAreceptors, in order to identify members of the general population as having an increased sensitivity to lower concentrations alcohol coupled with a decrease sensitivity to higher concentrations of alcohol, a scenario frequently found in patients suffering from alcoholism and premenstrual anxiety. Methods of screening for drugs which decrease expression of the α4β2δ subunit of GABAAare also provided.
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Bunner Bridget E
Dilworth & Barrese LLP
The Research Foundation of State University of New York
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