α,2,8-sialyltransferase

Details α,2,8-sialyltransferase α,2,8-sialyltransferase

2007-01-16

2007-01-16

Prouty, Rebecca (Department: 1652)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S320100, C435S440000, C435S091400, C435S193000, C435S325000, C435S252300, C435S252330, C536S023200

Reexamination Certificate

active

10430325

ABSTRACT:
The invention provides a novel α-2,8-sialyltransferase expressed by a gene cloned from animal cells, a cDNA coding for the α-2,8-sialyltransferase, a method of detecting, or suppressing the production of α-2,8-sialyltransferase by using the cDNA, a recombinant vector containing the DNA as an insert and cells harboring the recombinant vector as well as methods of preparing same. The α-2,8-sialyltransferase of the invention is useful, for example, in the production of carbohydrate chains having a useful physiological activity, for example the ganglioside GD3, and modifications thereof.

REFERENCES:
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