α-1,3-fucosyltransferase

Details α-1,3-fucosyltransferase α-1,3-fucosyltransferase

2006-08-22

2006-08-22

Prouty, Rebecca (Department: 1652)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S097000, C435S193000, C435S320100, C435S252300, C435S252330, C435S325000, C536S023200

Reexamination Certificate

active

07094530

ABSTRACT:
The invention provides a novel species of α-1,3-fucosyltransferase expressed by a gene cloned from animal cells, a cDNA coding for the α-1,3-fucosyltransferase, a method of detecting, or inhibiting the production of, the α-1,3-fucosyltransferase which involves the use of the cDNA, a recombinant vector containing the DNA as an insert, a cell harboring the recombinant vector, and a method of producing same. The α-1,3-fucosyltransferase of the invention is useful in the production of carbohydrate chains having useful physiological activity, for example sialyl Lewis x, and modifications thereof.

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