α1,2-fucosyltransferase and DNA encoding the same

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...

Reexamination Certificate

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C536S023100, C435S069100

Reexamination Certificate

active

10487357

ABSTRACT:
The present invention provides a protein having α1,2-fucosyltransferase activity, a DNA encoding the protein, a recombinant DNA comprising the DNA, a transformant comprising the recombinant DNA, a process for producing the protein having α1,2-fucosyltransferase activity using the transformant, and a process for producing a fucose-containing complex carbohydrate using the transformant.

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G. Wang et al., “Molecular Genetic Basis for the Variable Expression of Lewis Y Antigen inHelicobacter Pylori:Analysis of the α(1,2) Fucosyltransferase Gene”, Molecular Microbiology, 1999, vol. 31, pp. 1265-1274.
Monteiro, et al., “The Lipopolysaccharide ofHelicobacter mustelaetype strain ATCC 43772 expresses . . . ”, FEMS Microbiology Letters, vol. 154 (1997), pp. 103-109.
Albermann, et al., “Synthesis of the milk oligosaccharide 2′-fucosyllactose using recombinant bacterial enzymes”,Carbohydrate Research,vol. 334, No. 2 (2001), pp. 97-103.
Wang, et al., “NovelHelicobacterpylori α1,2-fucosyltransferase, a key enzyme in the synthesis of Lewis antigens”,Microbiology,vol. 145, No. 11 (1999), pp. 3245-3253.
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