α1,2 fucosyltransferase

Details α1,2 fucosyltransferase α1,2 fucosyltransferase

2006-08-22

2006-08-22

Saidha, Tekchand (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using a micro-organism to make a protein or polypeptide

C435S041000, C435S183000, C435S193000, C435S252300, C435S252330, C435S320100

Reexamination Certificate

active

07094578

ABSTRACT:
A bacterial α1,2-fucosyltransferase gene and deduced amino acid sequence is provided. The gene is useful for preparing α1,2-fucosyltransferase polypeptide, and active fragment thereof, which can be used in the production of oligosaccharides such as Lewis X, Lewis Y, Lewis B and H type 1, which are structurally similar to certain tumor-associated carbohydrate antigens found in mammals. These product glycoconjugates also have research and diagnostic utility in the development of assays to detect mammalian tumors.

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