Δ-9 desaturase and its use in making polyunsaturated...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S183000, C435S189000, C435S252300, C435S320100, C536S023200

Reexamination Certificate

active

07923223

ABSTRACT:
The present invention relates to a Δ9 desaturase, which has the ability to convert palmitic acid [16:0] or stearic acid [18:0] into palmitoleic acid [16:1] or oleic acid [18:1], respectively. Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding Δ9 desaturase along with a method of making long chain polyunsaturated fatty acids (PUFAs) using this Δ9 desaturase in oleaginous yeast is disclosed.

REFERENCES:
patent: 6448055 (2002-09-01), Shimizu et al.
patent: 6495738 (2002-12-01), Folkerts et al.
patent: WO 2006/052870 (2006-05-01), None
U.S. Appl. No. 10/840,478, filed Dec. 16, 2004, Stephen K. Picataggio et al.
U.S. Appl. No. 10/840,579, filed Jun. 23, 2005, Stephen K. Picataggio et al.
U.S. Appl. No. 10/840,325, filed Feb. 24, 2005, Narendra S. Yadav et al.
U.S. Appl. No. 10/869,630, filed Jan. 20, 2005, Stephen K. Picataggio et al.
U.S. Appl. No. 10/882,760, filed Jul. 20, 2006, Narendra S. Yadav et al.
U.S. Appl. No. 10/985,109, filed Jun. 16, 2005, Howard Glenn Damude et al.
U.S. Appl. No. 10/985,691, filed Sep. 29, 2005, Narendra S. Yadav et al.
U.S. Appl. No. 10/987,548, filed Jun. 16, 2005, Dana M. Walter et al.
U.S. Appl. No. 11/024,545, filed May 4, 2006, Zhixiong Xue et al.
U.S. Appl. No. 11/024,544, filed May 4, 2006, Narendra S. Yadav et al.
U.S. Appl. No. 11/166,993, filed Dec. 29, 2005, Howard Glenn Damude et al.
U.S. Appl. No. 11/183,664, filed Jan. 26, 2006, Stephen K. Picataggio et al.
U.S. Appl. No. 11/185,301, filed May 4, 2006, Zhixiong Xue et al.
U.S. Appl. No. 11/190,750, filed May 4, 2006, Stephen K. Picataggio et al.
U.S. Appl. No. 11/198,975, filed Aug. 8, 2005, Quinn Qun Zhu et al.
U.S. Appl. No. 11/225,354, filed Mar. 16, 2006, Zhixiong Xue et al.
U.S. Appl. No. 11/251,466, filed May 4, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 11/254,173, filed May 4, 2006, Daniel Joseph Macool et al.
U.S. Appl. No. 11/253,882, filed Apr. 19, 2007, Daniel Joseph Macool et al.
U.S. Appl. No. 11/264,784, filed May 4, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 11/264,737, filed May 25, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 11/265,761, filed Jun. 1, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 60/795,810, filed Apr. 28, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 60/793,575, filed Apr. 20, 2006, Zhixiong Xue et al.
U.S. Appl. No. 60/796,637, filed May 1, 2006, Narendra S. Yadav et al.
U.S. Appl. No. 60/801,172, filed May 17, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 60/801,119, filed May 17, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 60/853,563, filed Oct. 23, 2006, Howard Glenn Damude et al.
U.S. Appl. No. 60/855,177, filed Oct. 30, 2006, Zhixiong Xue et al.
U.S. Appl. No. 11/601,564, filed May 24, 2007, Howard Glenn Damude et al.
U.S. Appl. No. 11/635,258, filed Dec. 7, 2006, Howard Glenn Damude et al.
J. Dyerberg et al., Fatty Acid Composition of the Plasma Lipids in Greenland Eskimos, Amer. J. Clin. Nutr., 1975, vol. 28:958-966.
J. Dyerberg et al., Eicosapentaenoic Acid and Prevention of Thrombosis and Atherosclerosis, Lancet, 1978, vol. 2:117-119.
H. Shimokawa, Beneficial Effects of Eicosapentaenoic Acid on Endothelial Vasodilator Functions in Animals and Humans, World Rev. Nutr. Diet, 2001, vol. 88:100-108.
C. Von Schacky et al., 3 Fatty Acids—From Eskimos to Clinical Cardiology—What Took Us so Long?, World Rev. Nutr. Diet, 2001, vol. 88:90-99.
S. Smith, The Animal Fatty Acid Synthase: One Gene, One Polypeptide Seven Enzymes, FASEB J., 1994, vol. 8:1248-1259.
J.E. Stukey et al., The OLE1 Gene ofSaccharomyces cerevisiaeEncodes the 9 Fatty Acid Desaturase and Can Be Functionally Replaced by the Rat Stearoyl-CoA Desaturase Gene, J. Biol. Chem., 1990, vol. 265:20144-20149.
P.A. Meesters et al., Isolation and Characterization of a 9-Fatty Acid Desaturase Gene From the Oleaginous YeastCryptococcus curvatusCBS 570, Yeast, 1996, vol. 12:723-730.
National Center for Biotechnology Information General Identifier No. AB071696, Mar. 19, 2002, S. Kajiwara, Delta 9-Fatty Acid Desaturase Gene (SK-OLEI) ofSaccharomyces kluyveri.
S. Kajiwara, Molecular Cloning and Characterization PF the 9 Fatty Acid Desaturase Gene and Its Promoter Region FromSaccharomyces Kluyveri, FEMS Yeast Res., 2002, vol. 2:333-339.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Δ-9 desaturase and its use in making polyunsaturated... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Δ-9 desaturase and its use in making polyunsaturated..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Δ-9 desaturase and its use in making polyunsaturated... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2643588

All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.