X-ray contrast agent

Details X-ray contrast agent X-ray contrast agent

1992-06-25

1993-04-20

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

564153, C07C23746

Patent

active

052040860

ABSTRACT:
Compounds of the general formula: ##STR1## (wherein R represents --CH(CH.sub.2 OH).sub.2 or --CH.sub.2 CH(OH)CH.sub.2 OH) possess a package of favorable parameters which render them of particular use not only in all forms of intravascular visualization but also in myelography.
The compounds are prepared by reaction of the corresponding 5-monoacetylamino compound with one or more reagents effective to introduce the 2-hydroxy-3-methoxypropyl group.

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Weislander et al., Acta Radiologica (1987) Supplement, 370, pp. 73-77.
Halkala et al., Investigative Radiology, Sep. 1988, Suppl. 1, vol. 23, pp. 5200-5202.
Michelet, Acta Radiologica, 1987, 28, Fasc 3, pp. 329-333.
Almen, Acta Radiologica (1987) Supplement, 370, pp. 69-72.

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