Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-06-13
2006-06-13
Huff, Sheela J. (Department: 1643)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100, C435S069100, C435S320100, C530S350000
Reexamination Certificate
active
07060811
ABSTRACT:
The present invention provides the isolation and cloning of WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3–24.1, a region frequently affected in several cancers. This gene encodes a tumor suppressor with apoptotic functions. The invention provides WWOX nucleic acid- and polypeptide-based cancer therapies. The invention also provides methods for cancer detection, diagnosis and prognosis involving WWOX nucleic acids and polypeptides.
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GenBank Accession No. AF227527.
GenBank Accession No. AF227528.
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Aldaz C. Marcelo
Bednarek Andrzej
Board of Regents , The University of Texas System
Fulbright & Jaworski L.L.P.
Huff Sheela J.
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