WT1 monoclonal antibodies and methods of use therefor

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 71, 435 72, 435 721, 5303871, 5303877, 5303881, 5303888, 530809, G01N 33547, G01N 3353, C07K 1630, C07K 1618

Patent

active

056331428

ABSTRACT:
The present invention provides three unique monoclonal antibodies directed against a portion of the Wilms' tumor antigen, and methods of use therefor in detecting, monitoring and diagnosing malignancies characterized by over-expression or inappropriate expression of the WT 1 protein.

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