WT1 monoclonal antibodies

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Animal cell – per se – expressing immunoglobulin – antibody – or...

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5303873, 5303879, 5303881, 5303888, 53038885, 435 7021, 4351722, 435331, 435344, 4353441, C12N 512, C07K 1600, C07K 1618, C07K 1630

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056228350

ABSTRACT:
Three unique monoclonal antibodies, each having an epitope located in amino acids 1-181 of the WT1 tumor protein, and the hybridomas which secrete them have been constructed. These monoclonal antibodies are useful in the detection, monitoring, and diagnosis of malignancies characterized by inappropriate expression of the WT1 protein.

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