Wound healing formula

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

514 19, 514 21, 514 23, A61K 3805, A61K 3170

Patent

active

056565887

ABSTRACT:
The present invention provides a composition that stimulates and improves wound healing in a patient in need of same. To this end, a method for stimulating wound healing comprising the step of administering to a patient a composition including a therapeutically effective amount of a source of carnosine is provided. In an embodiment, the composition also meets the nutrient requirements of a patient that are generated due to tissue repair and healing requirements.

REFERENCES:
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patent: 4359416 (1982-11-01), Vinick
patent: 5164367 (1992-11-01), Pickart
patent: 5221668 (1993-06-01), Henningfield et al.
Ther. Res., vol. 13, No. 4, Kuwayama Hajime et al., 1992, abstract.
Fitzpatrick et al, Histamine synthesis, imidazole dipeptides, and wound healing, Surgery, vol. 91, No. 4, pp. 430-434 (1982).
Fitzpatrick et al, Carnosine, histidine, and wound healing, Surgery, vol. 91, No. 1, pp. 56-60 (1982).
Kunimi et al, Effects of CL-1700 on Duodenal Ulcer Formation in the Rat, Japan. J. Pharmacol. No. 32, pp. 1167-1170 (1982).
Kunimi et al, Effects of CL-1700 and Its Constituents on Acute or Chronic Gastric Lesions and Gastric Secretion in Rats, Japan. J. Pharmacol. No. 32, pp. 469-477 (1982).
Nagai et al, Action of carnosine and .beta.-alanine on wound healing, Surgery, vol. 100, No. 5, pp. 815-821 (1986).
Okabe et al, Effects of N-AcetylL-Carnosine Aluminum (CL-1700) on Various Acute Gastric Lesions and Gastric Secretion in Rats, Japan. J. Pharmacol. No. 31, pp. 941-950 (1981).
Vizioli et al, Effect of Carnosine on the Development of Rat Sponge-Induced Granulation I. General Morphology and Glycosaminoglycans Histophotometry, Cellular & Molecular Biology No. 23, pp. 267-273 (1978).

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