Wound healing composition of IL-1 and PDGF or IGF-1

Details Wound healing composition of IL-1 and PDGF or IGF-1 Wound healing composition of IL-1 and PDGF or IGF-1

1989-09-07

1991-07-30

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

514 12, 514 21, 530351, A61K 3736

Patent

active

050358871

ABSTRACT:
Healing an external wound of a mammal by administering to the mammal a composition containing purified platelet-derived growth factor and purified interleukin-1 or administering to the mammal a composition containing purified insulin-like growth factor and interleukin-1.

REFERENCES:
patent: 4801686 (1989-01-01), Kronheim
Martinet et al., J. Invest. Dermatol., 90: 122-126, 1988.
Bronson et al., Collagen Re. Res. 8: 199-208, 1988.
Grotendorst, J. Trauma 24: S49, (1984).
Leitzel et al., J. Dermatol. Surg. Oncol. 11: 617-22 (1985).
Michaeli et al., in Soft and Hard Tissue Repair, Hunt et al., eds., Praeger Publishers, N.Y., pp. 380-394, 1984.
Lynch et al., Proc. Natl. Acad. Sci. U.S.A. 84: 7696-7000, 1987.
Lynch et al., J. Clin. Invest. 84: 640-646, 1989.
Kaplan et al., Immunol. Res. 8: 118-129, 1989.

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