Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-08-31
2011-11-22
Padmanabhan, Sreeni (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S254010, C514S341000, C514S422000
Reexamination Certificate
active
08063052
ABSTRACT:
The present invention relates to the use of p38 MAP kinase inhibitors and p38 MAP kinase inhibition to promote wound healing.
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Saika S et al., “Role of p38 MAP Kinase in Regulation of Cell Migration and Proliferation in Healing Corneal Epithelium”,Investigative Ophthalmology and Visual Science 2004 United States, vol. 45, No. 1 (2004) pp. 100-109.
Stoll Stefan W et al., “Keratinocyte outgrowth from human skin explant cultures is dependent upon p38 signaling”,Would Repair and Regeneration, vol. 11, No. 5 (2003) pp. 346-353.
Sharma Guru-Dutt et al., “p38 and ERK1/2 coordinate cellular migration and proliferation in epithelial wound healing”,Journal of Biological Chemistry, vol. 278, No. 24 (Jun. 13, 2003) pp. 21989-21997.
Karol Jody
Morgan & Lewis & Bockius, LLP
Padmanabhan Sreeni
Systagenix Wound Management (US), Inc.
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