Surgery: splint – brace – or bandage – Bandage structure – Skin laceration or wound cover
Patent
1996-08-16
1998-03-03
Apley, Richard J.
Surgery: splint, brace, or bandage
Bandage structure
Skin laceration or wound cover
602 48, 602 54, A61F 500
Patent
active
057229422
DESCRIPTION:
BRIEF SUMMARY
In this specification, a "wound" means a scratch, lacerated wound, incised wound, bedsore, and burn.
The present invention relates to wound covering materials suitable for protection and treatment of wounds.
Japanese Patent Publication No. 2-34618 discloses a wound covering material which is formed by kneading glucomannan with or without other naturally occurring polysaccharides in a system comprising at least one compound selected from polyhydric alcohols, sugar alcohols, monosaccharides, disaccharides and oligosaccharides, dissolving the resulting mixture in water, and drying the solution into the form of a film.
This known wound covering material has certain favorable characters such as permeability to water vapor and oxygen, close fit to the wound surface and prevention of excess body fluid from accumulating on the wound surface, and resistance to biodegradation by the body fluid.
However, this wound covering material has low adhesiveness to a normal skin and has a nature to gradually lose its flexibility and elasticity after application to a wound site, thus leading to notable gross shrinking and hardening. Thus, this wound covering material often slides away or detaches from the wound surface, thereby losing its wound sealing and protective function, even when it is fixed onto an immobile part of the body by means of bandages or a surgical tape, let alone when applied to a curved or mobile part such as a joint area. The loss of wound sealing and protective function will lead to drying of the wound surface, resulting in notable retardation of epithelialization compared with wet healing materials used in wound healing in wet environment. Moreover, even if it remains in position over the wound surface, its gross hardening gives rise to the possibility of injury not only to the wound site but also normal tissues surrounding the site. Thus, there is a need to add an improvement to the mentioned known wound covering material.
In the field of food, there are a number of examples of uses of compositions containing glucomannan and pullulan or carrageenan.
For example, Japanese Patent Publication No. 1-59851 discloses food products containing glucomannan and carrageenan and the method for producing them. However, the method for production requires a temperature not lower than 50.degree. C. In contrast, the wound covering material of the present invention may be produced at room temperature. In addition, as the product provided by the above cited production method is intended for eating, it is required to be disintegrated or dissolved within the gastrointestinal tract after taken up, whereas the wound covering material of the present invention will not be dissolved or disintegrated after absorbing exudates from a wound.
Also, Japanese Patent Publication No. 5-49705 discloses a gradually disintegrating, pullulan-containing product which contains a heteromannan. The product, however, is intended for use as a coating membrane for food products and medications, and its major component is pullulan, the amount of the heteromannan contained being not more than the amount by weight of the pullulan contained. Thus, the product differs in the objective and composition from the wound covering material of the present invention which is used by directly applying onto the affected site for protection or healing of the wound.
On the other hand, while the physiologically acceptable adhesive polymer bases employed in the present invention have been utilized as adhesive components in a variety of cataplasms and plasters, it was not known that they confer flexibility and elasticity to the materials when they are incorporated in wound covering materials having glucomannan as the major component.
The objective of the present invention is to provide wound healing materials with prominent sealing and protective function on wound sites which possess adequate adhesiveness, flexibility and elasticity retained even after application onto the wound sites, while maintaining at the same time the favorable characteristics of the wound healin
REFERENCES:
patent: 4851394 (1989-07-01), Kobodera
patent: 5409703 (1995-04-01), McAnalley et al.
patent: 5429591 (1995-07-01), Yamamoto et al.
patent: 5558861 (1996-09-01), Yamanaka et al.
Harada Shoichi
Morimoto Yasuo
Tanaka Masaya
Yamashita Sadashi
Apley Richard J.
Kanebo Ltd.
Lee Kim M.
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