Wound and cutaneous injury healing with a nucleic acid...

Details Wound and cutaneous injury healing with a nucleic acid... Wound and cutaneous injury healing with a nucleic acid...

2006-11-27

2009-02-10

Crouch, Deborah (Department: 1632)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C424S093200, C424S093210

Reexamination Certificate

active

07488719

ABSTRACT:
A description of a biomolecule named Perlecan which is added internally or topically, or is expressed from exogenously added nucleic acids, as a whole or in part, to a healing wound to improve the success of wound healing is disclosed. Relevant embodiments for this patent technology are described.

REFERENCES:
patent: 6524573 (2003-02-01), Iozzo
patent: 7029668 (2006-04-01), Simons
patent: 7141551 (2006-11-01), DeCarlo
patent: WO 99/06054 (1999-02-01), None
Groffen et al. Expression and Characterization of Human Perlecan Domains I and II Syntesized by Baculovirus-Infected instect Cells. Eur.J. Biochem. 241, pp. 827-834, 1996.
Nugent et al. Fibroblast Growth Factor-2. International J. Biochem. Cell Viol. 2000, vol. 32 pp. 115-120.
Zhao,e al Adenovirus-Mediated Decorin Gene Transfer Prevents TGF-Beta Induced Inhibition of Lung Morphogenesis. American.J.Physiol., vol. 277(Lung Cell. Mol. Phys.21) pL412-422, 1999.
International Application, WO 02/17955 A1, Mar. 7, 2002.

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