WNV core protein/capsid interacting protein and uses of the...

Chemistry: molecular biology and microbiology – Vector – per se

Reexamination Certificate

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C435S325000, C435S252300, C536S023500, C536S024310

Reexamination Certificate

active

07625751

ABSTRACT:
Substantially pure WIP-1 and its use in assays to identify PAP-1/WIP-1 interaction inhibitors or WIP-I/WNV Cp interaction inhibitors are disclosed. Compositions comprising antisense sequences to prevent expression of WIP-1 and methods of treating cancer using the same are disclosed.

REFERENCES:
patent: 6031151 (2000-02-01), Draper
patent: 1033401 (2000-09-01), None
Fiscella et al., “Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner,” PNAS, vol. 94, pp. 6048-6053 (1997).
Bressan et al., “Repeating Structure of Chick Tropoelastin Revealed by Complementary DNA Cloning,” Biochemistry, vol. 26, No. 6 (1987).
NCBI Blast nucleotide search result, Accession No. AE014298 (search was run 2007).
NCBI Blast nucleotide search result, Accession No. M15889.1 (search was run 2007).
SCORE sequence search result 14, 3.rng (2007).
Genome Research 8:1097-1108, 1998 (no author listed).
Accession No. NM—031288, Sep. 24, 2005.
Genbank AW594669, Mar. 22, 2000.
EMBL Acc. No. AB054538 from Ariga, et al., “Homo spaiensmRNA for PAPA-1, complete cds,” Jan. 21, 2001.
EMBL Acc. No, AW594669 from National Cancer Institute Genome Anatomy Project, “Homo sapienscDNA clone,” Mar. 3, 2000.
Ramanathan, et al., “Identification of a novel cellular receptor protein, Wip as a ligand for the West Nile Virus capsid,” Abstracts of the General Meeting of the American Society for Microbiology, (2002) 102:474.
Takekawa, et al., “p-53 inducible Wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signalling in response to UV radiation,” EMBO J. (2000) 19:6517-6526.
Choi, et al., “The structure and expression of the murine wildtype p53-induced phosphatase 1 (Wip1) gene,” Genomics (2000) 64:298-306.
Sambrook, et al.,Molecular Cloning: A Laboratory Manual, Second Ed. (New York: Col Spring Harbor Press, 1989).
Innis, M.A., et al., Eds.,PCR Protocols: A Guide to Methods and Applications(San Diego, CA: Academic Press, Inc., 1990).
Erlich, H.A., et al., Eds., “Polymerase Chain Reaction” (Cold Spring Harbor, NY: Cold Spring Harbor Press, 1989).
Accession No. NM 018739 (PAP-1; Mouse), Nov. 17, 2006.
Accession No. D78255 (PAP-1; Mouse), Feb. 1, 2003.
Accession No. M24779 (PIM-1; Human), Nov. 16, 1995.
Accession No. NM 002648 (PIM-1; Human), Nov. 17, 2006.
Accession No. XM 004317 (PIM-1; Human), Apr. 16, 2001.
Accession No. AB054538 (PAPA-1 (WIP-1)); Human), Nov. 18, 2006.
Accession No. NM 031288 (Papa-1 (WIP-1)); Human), Nov. 18, 2006.
Accession No. AF202541 (strain HNY1999), Dec. 16, 1999.
Accession No. NC 001563 (complete genome), Nov. 2, 2006.
Harlow, E. and Lane, D.,Antibodies: A Laboratory Manual(Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1988).

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