Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds hormone or other secreted growth regulatory factor,...
Reexamination Certificate
2008-11-21
2011-10-25
Romeo, David (Department: 1647)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds hormone or other secreted growth regulatory factor,...
C424S142100, C424S182100, C530S388150, C530S388240
Reexamination Certificate
active
08043620
ABSTRACT:
The present invention relates to binding agents for WISE, and includes for their manufacture and use.
REFERENCES:
patent: 2008/0160060 (2008-07-01), Ellies
patent: 02/08284 (2002-01-01), None
Clackson et al. Making antibody fragments using phage display libraries. Nature. Aug. 15, 1991;352(6336):624-8.
Portolano et al. Lack of promiscuity in autoantigen-specific H and L chain combinations as revealed by human H and L chain “roulette”. J Immunol. Feb. 1, 1993;150(3):880-7.
Abstract “Human angiogenesis related protein PRO532 Seq Id No. 70” (Jul. 19, 2002).
Yanagita, et al., “Uterine sensitization-associated gene-1 (USAG-1), a novel BMP antagonist expressed in the kidney, accelerates tubular injury” J of Clinical Investigation (Jan. 1, 2006) pp. 70-79 vol. 116, 3.
Yanagita, et al., “Balance Between Bone Morphogenetic Proteins and Their Antagonist in Kidney Injury” J of the International Society for Apheresis; (Oct. 1, 2007) pp. 538-543 vol. 11, 1.
Yanagita, et al., “USAG-1:a bone morphogenetic protein antagonist abundantly expressed in the kidney” Biochemical & Biophysical Research Communications (Apr. 2, 2004) pp. 490-500 vol. 316, 2.
Graham Kevin
Qian Xueming
Shimamoto Grant
Tipton Barbara S.
Tsai Mei-Mei
Amgen Inc.
Mohr Randolph M.
Romeo David
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