Win 49596-finasteride method of use and compositions

Details Win 49596-finasteride method of use and compositions Win 49596-finasteride method of use and compositions

1991-10-07

1992-12-29

Goldberg, Jerome

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514284, A61K 3158, A61K 3144

Patent

active

051751550

ABSTRACT:
The method of use of a combination of the antiandrogen (5.alpha.,17.alpha.)-1'-(methylsulfonyl)-1'H-pregn-20-yno[3,2-c]pyrazol-17 -ol (Win 49596) and the 5.alpha.-reductase inhibitor (5.alpha.,17.beta.)-N-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carb oxamide (finasteride) for treating prostate disease in a male mammal and pharmaceutical compositions thereof are disclosed.

REFERENCES:
patent: 4684636 (1987-08-01), Christiansen et al.
patent: 4760071 (1988-07-01), Rasmusson et al.
USAN and the USP Dictionary of Drug Names, 1991, p. 257.
Labrie et al., Endocrinology, vol. 128, No. 3, pp. 1673-1675, 1991.

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