Chemistry: molecular biology and microbiology – Vector – per se
Patent
1993-09-01
1996-11-26
Chambers, Jasemine C.
Chemistry: molecular biology and microbiology
Vector, per se
4351723, 435183, 435196, 536 235, 536 2431, 935 23, 935 24, 935 29, 935 9, C07H 2100, C12N 900, C12N 1512, C12N 1563
Patent
active
055784933
ABSTRACT:
This invention provides an isolated, vertebrate nucleic acid molecule encoding the normal protein that prevents development of Wilson's disease. This invention also provides a nucleic acid molecule comprising a nucleic acid molecule of at least 15 nucleotides capable of specifically hybridizing with a sequence included within the sequence of the above-described nucleic acid molecule. Finally, this invention provides various uses of the isolated Wilson's disease gene.
REFERENCES:
Kooy et al. 1993 Human Genetics 91:504-506.
Vulpe et al. 1993. Nature Genetics 3:7-13.
Chelly et al. 1993. Nature Genetics 3:14-19.
Mercer et al. 1993. Nature Genetics 3:20-25.
Chelly et al. 1993. Nature Genetis 5:317-318.
Bull et al. 1993 Nature Genetics 5:327-337.
Petrukhin et al. 1993. Nature Genetics 5:338-343.
Tanzi et al. 1993. Nature Genetics 5:344-350.
Yamaguchi et al. 1993. Biochem. Biophys. Res. Comm. 197(1):271-277.
Watson, 1993. Tibtech 11:114-117.
Gilliam T. Conrad
Tanzi Rudolph E.
Chambers Jasemine C.
General Hospital Corporation
Stanton Brian R.
The Trustees of Columbia University in the City of New York
White John P.
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