Whole blood separation method and devices using the same

Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...

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210483, 210488, 210489, 210490, 210496, 210503, 210504, 210505, 210506, 210508, 210767, 422 55, 422 56, 422 57, 422 60, 422 73, 422101, 422102, 422169, 422170, 422177, 422178, 530412, 530415, B01D 3700, B01D 3900, G01N 3348, G01N 3350

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active

057257744

ABSTRACT:
The present invention relates to a method and to a device for separating plasma from whole blood. The method and device utilize a permeable non-glass fiber matrix containing a polyol which is capable of clumping red blood cells. The matrix, in the absence of such a polyol, would otherwise be porous to red blood cells. The polyol-containing matrix has a first surface and a second surface such that a whole blood sample which is applied to the first surface flows directionally toward the second surface. Plasma separated from whole blood becomes available at the second surface of the matrix and can be tested for the presence of a particular analyte, such as glucose or fructosamine, as provided by multi-layer test devices of the present invention.

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Dialog Database Abstract of EPA 0 194 502 to Limbach and Helger, EPA published Sep. 17, 1986.

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