Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1994-07-15
1997-06-10
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 71, 436 63, 436536, C12Q 170, G01N 3353, G01N 3348, G01N 33536
Patent
active
056374534
ABSTRACT:
The present invention relates to an improved method and kit for the detection of antibodies directed against the human immunodeficiency virus (HIV) in whole blood obtained from individuals who are HIV-seronegative as determined by conventional assay techniques. Whole blood is isolated from these individuals and cultured directly with mitogen to stimulate the proliferation of B-lymphocytes producing immunoglobulin specific for HIV. This method provides a rapid, simple, and inexpensive means for screening large numbers of blood samples for HIV infection while minimizing exposure of the technician to infectious blood components.
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Nucker Christine M.
Parkin Jeffrey S.
Shiloov Medical Technologies, Ltd.
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