Whole blood glucose test strip

Details Whole blood glucose test strip Whole blood glucose test strip

1995-03-21

1996-10-08

Gitomer, Ralph J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving glucose or galactose

435805, 435808, 422 56, 422 58, C12Q 154, G01N 2100, G01N 2177

Patent

active

055630421

ABSTRACT:
A whole blood glucose test strip for measuring glucose in an unmeasured whole blood sample which does not require removal of excess sample, and which is adapted for use in a reflectance reading apparatus which measures reflectance at about 635 nm and about 700 nm, the test strip comprising a handle having an aperture defined therein; and a porous, hydrophilic matrix disposed over the aperture such that one surface of the matrix is exposed to the atmosphere adjacent to one side of the strip and the other surface of the matrix is exposed to the atmosphere on the other side of the strip through the aperture, one of the surfaces being an upper sample receiving surface adapted to receive the whole blood sample on one side of the matrix and the second of the surfaces being a lower testing surface from which diffuse reflected light is measurable, the testing surface being opposite to the sample receiving surface. The matrix allows the blood color of the blood sample to be observed from the testing surface, allows at least a portion of the blood sample to penetrate through the matrix from the sample receiving surface to the testing surface, and filters out red blood cells such that they do not reach the testing surface. The matrix comprises reagent means for chemically reacting with glucose to create a change in reflectance which is indicative of the concentration of glucose present in the sample.

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