Whole blood analysis of prostate specific antigen spotted on a s

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

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435968, 435975, 435 21, C12Q 100, C12Q 142, G01N 3353

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active

059357754

ABSTRACT:
The present invention provides for the measurement of prostate specific antigen (PSA) from extracts of blood dried on a suitable solid support. PSA in solid support dried blood is stable for more than 100 days at room temperature. The procedure of the present invention can reliably distinguish normal from elevated levels of PSA and that facilitates screening and monitoring to detect disease in large scale mail-in programs to centralized laboratories.

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patent: 5190049 (1993-03-01), Briggs et al.
Ito et al; Japan J. Clin. Pathol.; vol. 42, pp. 539-543, 1994, Month not available. Please print.
Armbruster, "Prostate-Specific Antigen: Biochemistry, Analytical Methods, and Clinical Application," Clin. Chem. Feb. 1993, 39, 181-195, Month not available. Please print.
Watanabe H. et al., PSA Assay of Dried Blood Samples From the Ear Lobe on a Filter Paper with Special Reference to Prostatic Mass Screening, Prostate 27:90-94 (Aug. 1995).
Derwent WPI Abstract of JP 7098315A for Simple and Easy Determination of Prostate-specific Antigen--by Extracting Analyte Component Containing the Antigen from Part (s) of Support Holding Blood Components. (1995) Month not available.

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