Whole blood analyses in porous media

Details Whole blood analyses in porous media Whole blood analyses in porous media

1978-08-24

1981-02-10

Turk, Arnold

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

23230R, 23230B, 422 56, 422 58, 422 66, 422 69, 435291, 435299, 435805, C12M 134, G01N 2127, G01N 3106, G01N 3352

Patent

active

042502578

ABSTRACT:
Method and apparatus for analyzing whole blood samples which feature impregnating a gel medium used for the analysis of the whole blood sample with an inert substance. When the whole blood sample is placed on the gel medium, the inert substance diffuses from the gel as the plasma solutes of the blood diffuse into the gel. The amount of the inert substance diffusing from the gel medium is inversely proportional to the hematocrit of the blood sample. In one embodiment, plasma solutes are caused to react with one or more reagents in the gel medium to assay various specific analytes. Also, the hematocrit, indicated by the diffusion rate of the inert substance from the gel, is determined and used to correct such assay.

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