Whitening cosmetic preparation and method of using same

Details Whitening cosmetic preparation and method of using same Whitening cosmetic preparation and method of using same

1994-04-22

1997-12-16

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Bleach for live hair or skin

424401, A61K 748

Patent

active

056981856

ABSTRACT:
A whitening cosmetic preparation containing angiogenin as an effective component is disclosed. Angiogenin used in the present invention may be derived from milk, especially bovine milk. The whitening cosmetic preparation contains at least 0.001% by weight, preferably from 0.01 to 20% by weight angiogenin based on the total amount of said preparation. A method for whitening skin comprising administration of angiogenin to skin is also disclosed. The whitening cosmetic preparation inhibits melanin production and prevents the developments of blotches and freckles of skin.

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Biochemistry, 1988, American Chemical Society, pp. 6282-6287, "Isolation of Bovine Agiogenin using a Placental Ribonuclease Inhibitor Binding Assay" M.D. Bond, et al.
Biochemistry, 1985, American Chemical Society, pp. 5486-5494, "Amino Acid Sequence of Human Tumor Derived Angiogenin", D. J. Strydom, et al.
Biochemistry 1985, American Chemical Society, pp. 5480-5486, "Isolation and Characterization of Angiogenin, an Angiogenic Protein from Human Carcinoma Cells", J.W. Fett, et al.
Analytical Biochemistry 173, (1988); "An In Vitro Binding Assay For Angiogenin Using Placental Ribonuclease Inhibitor"; Michael D. Bond.

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