Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2010-09-23
2011-10-04
Pak, Michael (Department: 1646)
Chemistry: molecular biology and microbiology
Vector, per se
C435S325000, C536S023500
Reexamination Certificate
active
08030067
ABSTRACT:
The present invention relates to a novel isolated whitefly ecdysone receptor polypeptide. The invention also relates to an isolated nucleic acid encoding the whitefly ecdysone receptor polypeptide, to vectors comprising them and to their uses, in particular in methods for modulating gene expression in an ecdysone receptor-based gene expression modulation system and methods for identifying molecules that modulate whitefly ecdysone receptor activity.
REFERENCES:
patent: 4631211 (1986-12-01), Houghten
patent: 4859609 (1989-08-01), Dull et al.
patent: 4981784 (1991-01-01), Evans et al.
patent: 4985461 (1991-01-01), Hsu et al.
patent: 5010175 (1991-04-01), Rutter et al.
patent: 5117057 (1992-05-01), Hsu et al.
patent: 5225443 (1993-07-01), Murphy et al.
patent: 5283173 (1994-02-01), Fields et al.
patent: 5378726 (1995-01-01), Yanagi et al.
patent: 5459127 (1995-10-01), Felgner et al.
patent: 5514578 (1996-05-01), Hogness et al.
patent: 5530028 (1996-06-01), Lidert et al.
patent: 5710004 (1998-01-01), Evans et al.
patent: 5723329 (1998-03-01), Mangelsdorf et al.
patent: 5880333 (1999-03-01), Goff et al.
patent: 6013836 (2000-01-01), Hsu et al.
patent: 6096787 (2000-08-01), Evans et al.
patent: 6245531 (2001-06-01), Hogness et al.
patent: 6265173 (2001-07-01), Evans et al.
patent: 6281330 (2001-08-01), Evans et al.
patent: 6333318 (2001-12-01), Evans et al.
patent: 6379945 (2002-04-01), Jepson et al.
patent: 6458926 (2002-10-01), Evans et al.
patent: 6723531 (2004-04-01), Evans et al.
patent: 6756491 (2004-06-01), Evans et al.
patent: 6958236 (2005-10-01), Pascal et al.
patent: 7038022 (2006-05-01), Evans et al.
patent: 7045315 (2006-05-01), Evans et al.
patent: 7057015 (2006-06-01), Gage et al.
patent: 7091038 (2006-08-01), Palli et al.
patent: 7119077 (2006-10-01), Evans et al.
patent: 7563879 (2009-07-01), Palli
patent: 7601508 (2009-10-01), Palli et al.
patent: 7829676 (2010-11-01), Zhang et al.
patent: 2002/0110861 (2002-08-01), Dhadialla et al.
patent: 2002/0119521 (2002-08-01), Palli et al.
patent: 2004/0033600 (2004-02-01), Palli et al.
patent: 2004/0096942 (2004-05-01), Kapitskaya et al.
patent: 2004/0197861 (2004-10-01), Palli
patent: 2004/0235097 (2004-11-01), Zhang et al.
patent: 2005/0266457 (2005-12-01), Palli et al.
patent: 2006/0100416 (2006-05-01), Palli et al.
patent: 2008/0051344 (2008-02-01), Palli et al.
patent: 2008/0064097 (2008-03-01), Palli
patent: 2008/0214790 (2008-09-01), Palli
patent: 2008/0268499 (2008-10-01), Zhang et al.
patent: 2008/0280321 (2008-11-01), Palli
patent: 234994 (1987-09-01), None
patent: 461809 (1991-12-01), None
patent: 8912690 (1989-12-01), None
patent: 9200252 (1992-01-01), None
patent: 9428028 (1994-12-01), None
patent: 9518863 (1995-07-01), None
patent: 9521931 (1995-08-01), None
patent: 9617823 (1996-06-01), None
patent: 9625508 (1996-08-01), None
patent: 9627673 (1996-09-01), None
patent: 9738117 (1997-10-01), None
patent: 9902683 (1999-01-01), None
patent: 9936520 (1999-07-01), None
patent: 9958155 (1999-11-01), None
patent: WO 01/02436 (2001-01-01), None
patent: 0170816 (2001-09-01), None
patent: 0229075 (2002-04-01), None
patent: 02066612 (2002-08-01), None
patent: 02066613 (2002-08-01), None
patent: 02066614 (2002-08-01), None
patent: 02066615 (2002-08-01), None
patent: 2005108617 (2005-11-01), None
Antoniewski C et al., The ecdysone response enhancer of the Fbp1 gene ofDrosophila melanogasteris a direct target for the EcR/USP nuclear receptor, Mol Cell Biol, (1994), 14:4465-74.
Ashburner M et al., Temporal control of puffing activity in polytene chromosomes, Cold Spring Herb Symp Quant Biol, (1974), 38:655-62.
Cherbas L et al., Identification of ecdysone response elements by analysis of theDrosophilaEip28/29 gene, Genes Dev, (1991), 5:120-31.
Cho WL et al., Mosquito ecdysteroid receptor: analysis of the cDNA and expression during vitellogenesis, Insect. Biochem Mol Biol, (1995), 25:19-27.
Chung AC et al., Cloning of crustacean ecdysteroid receptor and retinoid-X receptor gene homologs and elevation of retinoid-X receptor mRNA by retinoic acid, Mol Cell Endocrinol, (1998), 139:209-27.
D'Avino PP et al. The moulting hormone ecdysone is able to recognize target elements composed of direct repeats, Mol Cell Endocnnol, (1995), 113:1-9.
Dhadialla TS et al., New insecticides with ecdysteroidal and juvenile hormone activity, Annu Rev Entomol, (1998), 43:545-69.
Evans RM, The steroid and thyroid hormone receptor superfamily, Science, (1988), 240:889-95.
Fujiwara H et al., Cloning of an ecdysone receptor homolog fromManduca sextaand the developmental profile of its mRNA in wings, Insect Biochem Mol Biol, (1995), 25:845-56.
Godowski PJ et al., Signal transduction and transcriptional regulation by glucocorticoid receptor-LexA fusion proteins, Science, (1988), 241:812-6.
Guo X et al., Isolation of a functional ecdysteriod receptor homologue from the ixodid tickAmblyomma americanum(L.), Insect Biochem Mol Biol, (1997), 27:945-62.
Hannan GN et al., Cloning and characterization of LcEcR: a functional ecdysone receptor from the sheep blowflyLucillia cuprina, Insect Biochem Mol Biol, (1997), 27:479-88.
Heberlein U et al., Characterization ofDrosophilatranscription factors that activate the tandem promoters of the alcohol dehydrogenase gene, Cell, (1985), 41:965-77.
Imhof MO et al., Cloning of aChironomus tentanscDNA encoding a protein (cEcRH) homologous to theDrosophilia melanogasterecdysteriod receptor (dEcR), Insect Biochem Mol Biol, (1993), 23:115-24.
Kothapalli R et al., Cloning and developmental expression of the ecdysone receptor gene from the spruce budworm,Choristoneura fumiferana, Dev Genet, (1995), 17:319-30.
Koelle MR et al., TheDrosophilaEcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily, Cell, (1991), 67:59-77.
Martinez A et al., Transcriptional activation of the clonedHeliothis virescens(Lepidoptera) ecdysone receptor (HvEcR) by muristeroneA, Insect Biochem Mol Biol, (1999), 29:915-30.
Morrison DA et al., Isolation of transformation-deficientStreptococcus pneumoniaemutants defective in control of competence, using insertion-duplication mutagenesis with the erythromycin resistance determinant of pAM beta 1, J Bacteriol, (1984), 159:870-6.
Mouillet JF et al., Cloning of two putative ecdysteroid receptor isoforms fromTenebno molitorand their developmental expression in the epidermis during metamorphosis, Eur J Biochem, (1997), 248:856-63.
Neuberger MS et al., Recombinant References Cons antibodies possessing novel effector functions, Nature, (1984), 312:604-8.
Riddiford LM et al., Ecdysone receptors and their biological actions, Vitam Horm, (2000), 60:1-73.
Saleh DS et al., Cloning and characterization of an ecdysone receptor cDNA fromLocusta migratoria, Mol Cell Endocrinol, (1998), 143:91-9.
Karen S. Christopherson et al., “Ecdysteroid-dependent regulation of genes in mammalian cells by aDrosophilaecdysone receptor and chimeric transactivators”, Proc. Natl. Acad. Sci. U.S.A., 1992, 89: 6314-6318.
Suhr ST et al., High level transactivation by a modifiedBombyxecdysone receptor in mammalian cells without exogenous retinoid X receptor, Proc Natl Acad Sci U S A, (1998), 95:7999-8004.
Swevers L et al., The silkmoth homolog of theDrosophilaecdysone receptor (B1 isoform): cloning and analysis of expression during follicular cell differentiation, Insect Biochem Mol Biol, (1995), 25:857-66.
Verras M et al., Cloning and characterization of CcEcR. An ecdysone recepto homolog from the mediterranean fruit flyCeratitis capitata, Eur J Biochem, (1999), 265:798-808.
Wilson JM et al., Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits, J Biol Chem, (1992), 267:963-7.
David NO et al., “Ecdysone-inducible gene expression in mammalian cells and transgenic mice”, Proc. Natl. Acad. Sci., 1996, 93: 3346-3351.
D. Metzger et al., “The human oestrogen receptor functions in yeast”, Nature, 1988, 334:31-36.
Perring et al. (1993) Science 259:74-77.
Perring, T.M. et al., “Identi
Cress Dean Ervin
Dhadialla Tarlochan Singh
Palli Subba Reddy
Zhang Jianzhong
Intrexon Corporation
Pak Michael
Sterne Kessler Goldstein & Fox P.L.L.C.
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