Wettable ePTFE medical devices

Details Wettable ePTFE medical devices Wettable ePTFE medical devices

2010-11-15

2011-10-04

Yuan, Dah-Wei (Department: 1717)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Drug delivery

C204S164000, C606S041000, C604S265000, C604S230000, C623S001100, C623S001150, C623S001420

Reexamination Certificate

active

08029562

ABSTRACT:
Methods are provided for surface modifying a hydrophobic polymer substrate to increase wettability comprising the steps of pre-treating the hydrophobic polymer substrate with a radio frequency (RF)-generated first plasma and a RF-generated second plasma wherein the first plasma and the second plasma are applied sequentially, coating the hydrophobic polymer substrate with a hydrophilic coating; and polymerizing the hydrophilic coating on the hydrophobic polymer substrate by exposure to a RF-generated third plasma.

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Kitching, K.J., et al., “Modification of Microporous ePTFE Materials to Enhance Wettability”, 24th Annual S&T Conference, Abstract, 2005.
Kitching, K.J., et al., “Modification of Microporous ePTFE Materials to Enhance Wettability”, 24th Annual S&T Conference, Poster, 2005.
Zhang, Q., et al., “Biocompatibility evaluation of ePTFE membrane modified with PEG in atmospheric pressure glow discharge”, JJ Biomed. Mater. Res., vol. 60, pp. 502-509, 2002.
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Kitching, et al., Modification of Microporous ePTFE Materials to Enhance Wettability, 24th Annual S&T Conference, Poster, 2005.
Kitching, et al., Modification of Microporous ePTFE Materials to enhance Wettability, 24th annual S&T Conference, Abstract, 2005.
Zhang, et al., Biocompatibility Evaluation of ePTFE Membrance Modified with PEG in Atmospheric Pressure Glow Discharge, JJ. Biomde. Mater. Res., vol. 60:pp. 502-509, 2002.

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