Well-type diagnostic plate device

Details Well-type diagnostic plate device Well-type diagnostic plate device

1986-12-15

1989-01-10

Richman, Barry S.

Chemical apparatus and process disinfecting, deodorizing, preser

Control element responsive to a sensed operating condition

422102, 435 7, 435301, 356246, C12M 120

Patent

active

047972599

ABSTRACT:
A diagnostic test device is provided including a plate having at least one well, preferably a plurality of wells, each with an open bottom across which a composite membrane comprising three layers is placed, with a hydrophobic, liquid-tight seal provided at the periphery of each well. The composite membrane from the top of upstream side to the bottom or downstream side, in sequence, includes a first reaction or filtration layer formed from a thin, liquophilic, microporous membrane, a second or sealing layer, preferably a hydrophobic material in sheet or fiber form, such as nonwoven polypropylene fibers, and a liquophobic, preferably hydrophobic, barrier layer having one or more apertures which allows liquid to exit the well while eliminating lateral migration of a pendant liquid drop. The liquophobic seal provided by the liquophobic sealing layer eliminates "cross-talk" by lateral diffusion or wicking.

REFERENCES:
patent: 4066512 (1978-01-01), Lai et al.
patent: 4090850 (1978-05-01), Chen et al.
patent: 4246339 (1981-01-01), Cole et al.
patent: 4317726 (1982-03-01), Shepel
patent: 4407943 (1983-10-01), Cole et al.
patent: 4493815 (1985-01-01), Fernwood et al.

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