Chemical apparatus and process disinfecting – deodorizing – preser – Control element responsive to a sensed operating condition
Reexamination Certificate
2008-05-20
2008-05-20
Griffin, Walter D. (Department: 1797)
Chemical apparatus and process disinfecting, deodorizing, preser
Control element responsive to a sensed operating condition
Reexamination Certificate
active
10777581
ABSTRACT:
A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e.g., oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well.
REFERENCES:
patent: 6376233 (2002-04-01), Wolf et al.
patent: 6602716 (2003-08-01), Klimant
patent: 6673532 (2004-01-01), Rao
patent: 2002/0025547 (2002-02-01), Rao
patent: 2003/0219360 (2003-11-01), Olivier
patent: 1 580 261 (2005-09-01), None
patent: WO 02/26377 (2002-04-01), None
patent: WO 03/093406 (2003-11-01), None
Mohr, G.; Werner, T.; Wolfbeis, O. S. J. Fluoresc. (1995), 5: 135-138.
Bambot, S.B.; Holavanahali, R.; Lakowicz, J. R.; Carter, G. M.; Rao, G. Biotech. Bioeng. 43: 1139-1145 (1994).
Liebsch et al “Luminescence Lifetime Imaging of Oxygen, pH, and Carbon Dioxide Distribution Using Optical Sensors” in Applied Spectroscopy vol. 54, No. 4, from 2000.
M.M.Maharbiz, et al., “Microbioreactor Arrays with Parametric Control for High-Throughput Experimentation” Biotechnology and Bioengineering, vol. 85, No. 4, Feb. 20, 2004, p. 376-381.
N. Szita, et al., “Monitoring of Cell Growth, Oxygen, and pH in Microfermentors” in Micro Total Analysis Systems (m-TAS) 2002, Y. Baba, S. Shoji, and A. van den Berg (Eds.). Kluwer, Dordrecht, The Netherlands, 2002, pp. 7-9, as downloaded from http://jensengroup.mit.edu
ew—students on Feb. 10, 2004.
Michel Martin Maharbiz, “Electrochemical Gas Generation for Cell Culture”, PhD Dissertation, University of California Berkeley, May 2003, pp. 1-98.
Michel M. Maharbiz et al., “A Microfabricated Electrochemical Oxygen Generator For High-Density Cell Culture Arrays”, Solid-State Sensor, Actuator and Microsystems Workshop, Hilton Head Island, SC, Jun. 2-6, 2002, pp. 259-264.
Shabbir B. Bambot, et al., “Potential applications of lifetime-based, phase-modulation fluorimetry in bioprocess and clinical monitoring”, Tibtech Mar. 1995 (vol. 13), pp. 106-115.
European Search Report, dated Mar. 3, 2006.
Michel Martin Maharbiz, “Electrochemical Gas Generation for Cell Culture”, PhD Dissertation, University of California Berkeley, May 2003, pp. 99-170.
European Examination Report dated Dec. 28, 2006 for EP Application No. 05 250 761.1-1521 (3 pgs).
Response to Examination Report filed Apr. 23, 2007 in EP Application No. 05 250 761.1-1521.
Andronaco Gregory
Boyer Stephen G.
Klein David L.
Gener8, Inc.
Griffin Walter D.
Ramdhanie Bobby
Silicon Valley Patent & Group LLP
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