Weighted microsponge for immobilizing bioactive material

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 7021, 435 703, 4351721, 435174, 435176, 435177, 43524023, 43524024, 43524026, 4352523, 436548, 530356, 935 60, C12P 2100, C12N 1102, C12N 502, C12N 120

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051007835

ABSTRACT:
Weighted microsponges formed of a porous, biostable matrix of a biocompatible polymer containing an inert weighing material are prepared suitable for use in culturing organisms in motive reactor systems. The matrix has an open to the surface pore structure with an average pore size in the range of from about 1 to about 150 microns and the pores occupy from about 70 to about 98% by volume of the microsponge. The microsponges have an average particle size of from about 100 to about 1000 microns and a specific gravity of above about 1.05. Biocompatible polymers that can be used are polysaccharides, proteins and synthetic polymers and the weighing material can be metals, metal alloys, metal oxides or ceramics.

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