Weighted collagen microsponge for immobilizing bioactive materia

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435174, 435177, 43524023, 43524024, 43524026, 4352523, 436548, 530356, C12P 2100, C12N 1102, C12N 502, C12N 120

Patent

active

048617148

ABSTRACT:
Weighted collagen microsponges having a highly crosslinked collagen matrix are described suitable for use in culturing organisms in motive reactor systems. The microsponges have an open to the surface pore structure, and pore sizes and volumes suitable for immobilizing a variety of bioactive materials. The microsponges also have an average particle size in the range of about 100 to about 1000 microns and a specific gravity above about 1.05.

REFERENCES:
patent: 3242055 (1966-03-01), De Lucia
patent: 3628974 (1971-12-01), Battista
patent: 3649347 (1972-03-01), Battista
patent: 3681093 (1972-08-01), Tsuzuki et al.
patent: 3717551 (1973-02-01), Bizzini et al.
patent: 3838007 (1974-09-01), Van Velzen
patent: 3843446 (1974-10-01), Vieth et al.
patent: 3850751 (1974-11-01), Messing
patent: 3919048 (1975-11-01), Dahlmans et al.
patent: 3920593 (1975-11-01), Adama et al.
patent: 3928143 (1975-12-01), Coughlin et al.
patent: 3930951 (1976-01-01), Messing
patent: 3972776 (1976-08-01), Vieth et al.
patent: 3977941 (1976-08-01), Vieth et al.
patent: 3978855 (1976-09-01), McRae et al.
patent: 4004979 (1979-01-01), Avrameas et al.
patent: 4009286 (1977-02-01), Moll et al.
patent: 4036693 (1977-07-01), Levine et al.
patent: 4048018 (1977-09-01), Coughlin et al.
patent: 4060081 (1977-11-01), Yannas et al.
patent: 4061466 (1977-12-01), Sjoholm et al.
patent: 4063017 (1977-12-01), Tsao et al.
patent: 4066512 (1978-01-01), Lai et al.
patent: 4070246 (1978-01-01), Kennedy et al.
patent: 4070300 (1978-01-01), Moroni et al.
patent: 4071409 (1978-01-01), Messing et al.
patent: 4085203 (1978-04-01), Telling et al.
patent: 4090022 (1978-05-01), Tsao et al.
patent: 4092219 (1978-05-01), Lin et al.
patent: 4102746 (1978-07-01), Goldberg
patent: 4127447 (1978-11-01), Griffith et al.
patent: 4138290 (1979-02-01), McMullen et al.
patent: 4138292 (1979-02-01), Chibata et al.
patent: 4144126 (1979-03-01), Burbidge
patent: 4149936 (1979-04-01), Messing et al.
patent: 4153510 (1979-05-01), Messing et al.
patent: 4163691 (1979-08-01), Devos et al.
patent: 4169761 (1979-10-01), Precausta et al.
patent: 4177253 (1979-12-01), Davies et al.
patent: 4189534 (1989-02-01), Levine et al.
patent: 4203801 (1980-05-01), Telling et al.
patent: 4224413 (1980-09-01), Burbidge
patent: 4238480 (1980-12-01), Sawyer
patent: 4241176 (1980-12-01), Avrameas et al.
patent: 4250267 (1981-02-01), Hartdegen et al.
patent: 4266029 (1981-05-01), Branner-Jorgensen
patent: 4266032 (1981-05-01), Miller et al.
patent: 4279812 (1981-07-01), Cioca
patent: 4280954 (1981-07-01), Yannas et al.
patent: 4286062 (1981-08-01), Messing et al.
patent: 4287305 (1981-09-01), Compere et al.
patent: 4293654 (1981-10-01), Levine et al.
patent: 4303533 (1981-12-01), Fremont
patent: 4304857 (1981-12-01), Brouillard et al.
patent: 4305926 (1981-12-01), Everse et al.
patent: 4312946 (1982-01-01), Wood et al.
patent: 4321327 (1982-03-01), Chen et al.
patent: 4323650 (1982-04-01), Rosevear
patent: 4352887 (1982-10-01), Reid et al.
patent: 4373027 (1983-02-01), Berneman et al.
patent: 4373121 (1983-02-01), Cioca
patent: 4378017 (1983-03-01), Kosugi et al.
patent: 4384044 (1983-05-01), Kim et al.
patent: 4388331 (1983-06-01), Miller
patent: 4409247 (1983-10-01), Baret et al.
patent: 4412947 (1983-11-01), Ciocz
patent: 4415668 (1983-11-01), Siegel
patent: 4456685 (1984-06-01), Guthrie
patent: 4464468 (1984-08-01), Avrameas et al.
patent: 4479876 (1984-10-01), Fuchs
patent: 4591456 (1986-05-01), Huc et al.
patent: 4703108 (1987-10-01), Silver et al.
K. Nilsson et al., "Preparation of Immobilized Animal Cells", FEBS Letters, vol. 118, No. 1, pp. 145-150, Aug. 1980.
S. Reuveny, "Microcarriers in Cell Culture: Structure & Applications", Advances in Cell Culture, vol. 4, pp. 213-247, 218-19, 224-225, Academic Press (1985).
S. Karkare et al., "Continuous Fermentation with Fluidized Slurries of Immobilized Microorganisms", Bio/Technology, vol. 3, pp. 247-251 (Mar. 1985).
S. Karkare et al., "Immobilized Living Cell: Systems for the Production of Fuels and Biochemicals," presented at AICLE Diamond Jubilee Meeting, Washington, D.C., Oct. 30-Nov. 4, 1983.
Leighton, Journal of the National Cancer Institute, 12 (1951-52) pp. 545-551.
Jacobson et al., Biochimica et. Biophysica Acta, 506 (1978) pp. 81-96.
Kuo et al. (1981) In Vitro 17:901-906.
Van Wezel et al. (1983) In Vitro, 19:259.
Feder et al. (1983) In Vitro, 19:260.
Feder & Tolbert (1983), Scientific American 248:36-43.
Silman et al., Biopolymers, 4 (1966) pp. 441-448.
Karkare et al. (1984), "Continuous Production of Monoclonal Antibodies by Chemostatic and Immobilized Hybridoma Culture", American Chemical Society Annual Meeting, Aug. 27, 1984.
Encyclopedia of Polymer Science and Technology, vol. 1, (1964), pp. 186, 742-747.
Kolot, F. B., "Microbial Carriers-Strategy for Selection", Process Biochemistry, Aug./Sep. 1981.
Vieth et al., "Immobilized Microbial Cells in Complex Biocatalysis", American Chemical Society, 1979.
Venkatsubramanian, "Biocatalysis by Membrane-Attached Enzymes and Whole Microbial Cells", presented at the Symposium on Membrane Technology in the Eighties, Ystad, 1980.
Venkatasubramanian et al., "On the Mechanisms of Enzyme and Whole Microbial Cell Attachment to Collagen", J. Ferment. Technol., vol. 52, No. 4, pp. 268-278 (1974).
Venkatasubramanian et al., "Synthesis of Organic Acids and Modification of Steroids by Immobilized Whole Microbial Cells", Enzyme Engineering, vol. 3, (1978), pp. 29-41.
Venkatasubramanian et al., "Immobilized Microbial Cells", Progress in Industrial Microbiology, vol. 16, pp. 81-86 (1979).
Chemical Modification of Collagen Fibers with Carbodiimides, Chonan, Yasumasa; Matsunaga, Ayako; Toyoda, Harukazu (Leather Res. Inst., Tokyo Univ. Fuchu, Japan), Hikaku Kagaku 1974, 20(I), 29-36 (Japan).
Intracatenare Vernetzung von Gelatine mit Carbodiimide, Helvetica Chimica Acta-vol. 55, Fasc. 7 (1972)-Nr 247 pp. 2468.
Design of and Artificial Skin, I., Basic Design Principles, L. V. Yannas and John F. Burke Journal of Biomedical Materials Research, Vo. 14, 65-81 (1980).
Design of an Artificial Skin, II., Control of Chemical Composition, Yannas, Burke, Gordon, Huang, Rubenstein, Journal of Biomedical Materials Research, vol. 14, 107 131 (1980).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Weighted collagen microsponge for immobilizing bioactive materia does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Weighted collagen microsponge for immobilizing bioactive materia, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Weighted collagen microsponge for immobilizing bioactive materia will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2237953

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.