Weighted collagen microsponge for immobilizing bioactive materia

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide

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4351721, 435174, 435176, 435177, 43524024, 43524025, 43524026, 43524027, 4352521, 4352523, 436548, 530356, 935 60, C12P 2100, C12N 1102, C12N 502, C12N 1500

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048638560

ABSTRACT:
Weighted collagen microsponges having a highly crosslinked collagen matrix are described suitable for use in culturing organisms in motive reactor systems. The microsponges have an open to the surface pore structure, and pore sizes and volumes suitable for immobilizing a variety of bioactive materials. The microsponges also have an average particle size in the range of about 100 to about 1000 microns and a specific gravity above about 1.05.

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A.R. Tice et al., "Unfrozen Water Contents of Submarine Premafrost Determine By Nuclear Magnetic Resonance", Engineering Geology, vol. 18, pp. 135-146; 1981.
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A. R. Tice et al, "The Effects of Magnetic Particles on the Unfrozen Water Content of Frozen Soils Determined By Nuclear Magnetic Resonance", Soil Science, vol. 138, No. 1, pp. 63-73, Jul. 1984.

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